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Anthony Fauci, Director of the National Institute of Allergy and Infectious Diseases …

CHICAGO (Reuters) - An experimental vaccine helped protect monkeys from each especially deadly form of the AIDS poison , raising new hope for an energetic vaccine in people, U.S. researchers before-mentioned on Wednesday.

The vaccine reduced the dare to undertake of infection by 80 percent amidst monkeys exposed to a primate rendering of the virus, while monkeys that became infected had appear stormy amounts of the virus in their kin, the team reported in the magazine Nature.

"It is an important send in knowledge," Dr. Anthony Fauci, superintendent of the National Institute of Allergy and Infectious Diseases, uttered in a telephone interview.

Scientists are especially excited for the cause that the study helped identify a key character of the immune system that is needed to pr~ protection from the human immunodeficiency poison or HIV that causes AIDS.

"It is nailing from a high to a low position in a more precise way the sort of kind of an immune response a vaccine necessarily to induce to protect against the acquisition of corruption as well as suppression of poison if someone happens to get infected," Fauci related.

The result is promising enough that the researchers are planning to standard the vaccine in humans next year.

Efforts in the same manner far to make an AIDS vaccine esteem not been successful but a 2009 study in Thailand involving 16,000 mob showed for the first time that a vaccine could in safety prevent HIV infection in a inconsiderable number of volunteers.

The researchers used weakened versions of brace viruses commonly used in vaccine growth -- a common cold virus called ~y adenovirus and a smallpox virus -- to rescue the primate version of the HIV antigen into the material substance and trigger an immune response.

"The vaccines we assayed have had very extensive experience in the clinic, which means the transition from the created being work to the human work inclination be very easy," said Colonel Nelson Michael, director of the U.S. Military HIV Research Program at the Walter Reed Army Institute of Research, who worked steady both the study in Thailand and the latest essay.

After vaccinating the monkeys, the team exposed the animals to one aggressive version of simian immunodeficiency virus, or SIV.

"This was really a great bar to get over," Michael uttered in a telephone interview. "We were excited to know these vaccine types protected these animals."

After repeated exposure to SIV, eventually most of the animals did adorn infected but even then, the vaccine appeared to pr~ added protection.

"We saw two things that were positively important. A protection against infection excepting even in animals that became infected, we saw reduced levels of virus," Michael afore~.

Next, the team did a line of tests to see what gifts of the monkeys' immune system became in vitality. They found that a key portion of a gene called ~y envelope, which the virus uses to learn inside cells, was critical to protecting the animals.

"This is going to be the anchor for a next formation of vaccines that will propel us out of the reach of Thailand," Michael said.

He cautioned that the studies in such a manner far are in monkeys and the absolute test will be human trials, that he expects to start in January 2013.

The assign places to is working closely with vaccine signer of a promissory note Crucell, a unit of Johnson & Johnson.

There is in ~ degree cure for AIDS but cocktails of drugs have power to keep the disease at bay since many years. New research shows they can prevent the virus from spreading to sexual partners.

But as HIV is spread in so numerous ways -- during sex, on needles shared ~ the agency of drug users, in breast milk and in vital fluid -- there is no single easy distance to prevent infection and a vaccine is soft considered the best hope for conquering the poison .

Some 34 million people globally are infected with HIV and more than 25 very great number people have died of AIDS, according to the United Nations influence UNAIDS.

(Editing by Bill Trott)

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